Statistische Aussagekraft der Studien aus der Literaturliste

Gegenüberstellung der Anzahl der

  • 47,XXY-Teilnehmer (XXY),
  • Männer mit normalen Chromosomensatz (Kontroll) sowie
  • Sonstige bzw. weitere Gruppen (z.B. 47,XYY, 47,XXX, etc…)

Liste wird laufend ergänzt, Stand, 20. August 2014

Titel XXY Kontroll Sonstige
Lubienski A. et al, Evaluation of cognitive, affective and relation skills of adolescents treated with testosterone for 47 XXY Klinefelter syndrome 8!    
Patwardhan A.J. et al., Reduced Size of the Amygdala in Individuals with 47,XXY and 47,XXX Karyotypes 10 10 10 47,XXX
Ratcliffe SG et al, Prenatal testosterone levels in XXY and XYY males 20 29  
Ross J.L. et al, Behavioral and Social Phenotypes in Boys with 47,XYY Syndrome or 47,XXY Klinefelter Syndrome, 82 50 26 47,XYY
Samplaski MK et al., Phenotypic Differences in mosaic Klinefelter patients as compared with non-mosaic Klinefelter patients 86    
Tartaglia NR et al., Attention-deficit hyperactivity disorder symptoms in children and adolescents with sex chromosome aneuploidy: XXY, XXX, XYY and XXY 56   insgesamt 111
Van Rijn et al, Psychophysiological Markers of Vulnerability to Psychopathology in Men with an Extra X Chromosome (XXY) 14 15  
Bruining H et al., In search for significant cognitive features in Klinefelter syndrome through cross-species comparison of a supernumary X chromosome 34 90  
Bryant Daniel M. et al., Neuroanatomical Phenotype of Klinefelter Syndrome in Childhood: A Voxel-based morphometry study 31 36  
Skakkebaek A. et al., Neuropsychology and brain morphology in Klinefelter syndrome – the impact of genetics 73 73  
Skakkebaek A. et al., Neuroanatomical correlates of Klinefelter syndrome studied in relation to the neuropsychological profile 65 65  
Bishop D.V.M. et al., Autism, language and communication in children with sex chromosome trisomies 19   58 XXX, 58 XYY
Brandenburg-Goddard MN. et al., A comparison of neural correlates underlying social cognition in Klinefelter syndrome and autism, 14 19 17 Autisten
Bruining H. et al., Psychiatric Characteristics in a self-selected sample of boys with Klinefelter Syndrome 51    
Cederlöf M. et al., Klinefelter syndrome and risk of psychosis, autism and ADHD 860 86 000  
Cordeiro L. et al., Social Deficits in Male Children and Adolescents with Sex Chromosome Aneuploidy: A comparison of XXY, XYY and XXYY syndrome 102   40 XYY, 32 XXYY
Van Rijn S. et al., Social Behaviour and autistic traits in a sex chromosomal disorder: Klinefelter (47 XXY) syndrome 31 20/24  
Van Rijn et al., Vulnerability for autism traits in boys and men with an extra X chromosome (47, XXY): The mediating role of cognitive flexibility 71 61  
Van Rijn et al., Neural systems for social cognition in Klinefelter syndrome (47,XXY): evidence from fMRI 13 18  
Van Rijn et al., Social attentation, Affective Arousal and Empathy in Men with Klinefelter Syndrome (47,XXY): Evidence from Eyetracking and Skin conductance, 17 20  
Van Rijn et al., Social cognition and underlying cognitive mechanisms in children with an extra X chromosome : a comparison with autism spectrum disorder 29 88 17 Mädchen mit Trisomie X, 56 Autisten

Grundsätzliche Schlussfolgerungen: 

Je größer die Zahl der Teilnehmer, desto aussagekräftiger die Schlussfolgerungen der jeweiligen Studie. Entscheidend ist vor allem die Zahl der Klinefelter-Teilnehmer.

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